JELIDO

Get to know JELIDO®

About JELIDO®

JELIDO® (lidocaine hydrochloride jelly) is a topical jelly that is used in adults and children (2 years of age and older) to lubricate and numb (produce a temporary loss of feeling) the skin. It is used:

  • By your doctor before certain types of medical procedures
  • To help relieve pain from inflammation of the bladder and urethra

Do not use JELIDO® if:

  • You are allergic to:
    • Lidocaine, prilocaine, or to any other type of anaesthetic ending in “-caine”
    • Any of the other ingredients in JELIDO® (see list of non-medicinal ingredients)
  • You have a blood disorder called methemoglobinemia
  • You have a condition called glucose-6-phosphate dehydrogenase deficiency
  • You are treating an infant ≤ 12 months of age who is taking medicines that may cause the blood disorder called methemoglobinemia (e.g., sulfonamides)
Speak to your doctor to find out if JELIDO® is right for you.

How to use JELIDO®

JELIDO® can be:

  • Applied by the doctor when you or your child arrives for the medical procedure
  • For your own use, in certain conditions:
    • Pain caused by inflammation of the urethra or urinary bladder
    • Self-catheterization

When used by a healthcare professional:

  • Your dose or your child’s dose will depend on:
    • What part of the body JELIDO® will be applied to
    • Age, any health or medical conditions, and any medications you or your child are taking

When treating yourself or your child:

  • Do not use JELIDO® in greater amounts, more frequently, or for longer than instructed by your doctor or the package directions. This may cause unwanted and serious side effects.
  • Apply JELIDO® only to the area recommended by your healthcare professional. Do not apply to damaged skin unless directed by your healthcare professional. If you have a special skin condition or other conditions that require a doctor’s supervision, talk to your doctor before you use JELIDO®.
  • JELIDO® should start to work within 5 to 15 minutes after you apply it. The numbing effect usually lasts 20 to 30 minutes.
  • Clean the area well, before each application of jelly.
  • Avoid contact with eyes.

Children’s dose (2 years of age and older)

  • Follow the doctor’s instructions on how much of the jelly to use, how often it should be applied to the affected area, and how to apply it.
  • The dose will depend on the child’s weight.
    • No more than 3 mL of jelly per 10 kg of the child’s weight should be used per dose.
    • Do not use more than 4 doses in a period of 24 hours.

Step-by-step instructions for self-catheterization

Follow these directions carefully

The following are general directions for the maximum amount of JELIDO® that should be used in adults without a doctor’s supervision.

Adult dose

  • For use in the urethra before insertion of urinary catheters:
    • 5 to 20 mL is recommended as usually safe.
    • A usual adult dose is one 11 mL syringe, with possibly an additional syringe of 6 or 11 mL.
  • For use in the urethra and bladder:
    • Your doctor may use as many as 4 syringes (40 mL).

  1. STEP 1

    Wash your hands thoroughly with warm water and soap.

  2. STEP 2

    Remove the syringe from its sterile package by peeling back the paper backing where indicated by the red arrows.

  3. STEP 3

    Prepare the materials you will need and ensure they are within arm’s reach.

  4. STEP 4

    Position yourself either standing or seated on a toilet.

  5. STEP 5

    Clean the urethral area using a clean washcloth or an antiseptic wipe.

  6. STEP 6

    Before removing the cap from the end of the syringe, free the plunger by gently pressing it and then remove the cap.

  7. STEP 7

    Force a small amount (i.e., 1 cm) of JELIDO® out of the syringe.

    Inspect the syringe and jelly to ensure that there is no particulate matter, precipitation, discolouration, or leakage prior to administration.

    Do not administer if you see particles, discolouration, or leakage.

  8. STEP 8

    Adult females
    • Insert the tip into the opening of the urethra and press the plunger slowly to push out the gel.

    Adult males
    • Insert the tip into the opening of the urethra and press the plunger slowly to push out the gel.

  9. STEP 9

    The gel should start to work within 5–15 minutes after being applied. Do not insert the catheter until you feel the numbing or tingling effect.

The product should start to work within 5–15 minutes of applying it.

Additional information

  • Do not use more than 4 doses in a 24-hour period.
  • The syringe is for single use only. If the contents are not completely used, the syringe and remaining gel must be thrown away.
  • This medicine has been prescribed for your or your child’s current medical condition. Do not give it to other people.

Frequently asked questions

What are the ingredients in JELIDO®?

Medicinal ingredients: lidocaine hydrochloride 2%
Non-medicinal ingredients: Hypromellose USP, purified water, and sodium hydroxide (to adjust the pH).

What dosage form does it come in?

JELIDO® comes in a single-use syringe, in two package sizes: 6 mL and 11 mL.

How do I use JELIDO®?

See our step-by-step instructions on how to use JELIDO® above.

How does JELIDO® work?

JELIDO® (lidocaine hydrochloride jelly) belongs to a group of medicines called topical anaesthetics. Topical anaesthetics block nerve signals. This causes a temporary loss of feeling or numbness in the area where the jelly has been applied.

What side effects should I look out for, and what do I do about them?

These are not all the possible side effects that you may feel when taking JELIDO®. If you experience any side effects not listed here, contact your healthcare professional.

Stop taking JELIDO® and get immediate medical help if the following occur:

Allergic reaction (rare): Difficulty swallowing or breathing, wheezing, drop in blood pressure, feeling sick to your stomach and throwing up, hives or rash, swelling of the face, lips, tongue, or throat.

Methemoglobinemia (rare): Brownish or greyish skin, especially around lips and nails.

Extremely rare: Drowsiness, numbness of your tongue, light-headedness, ringing in your ears, blurred vision, vomiting, dizziness, unusually slow heartbeat, fainting, nervousness, unusual sweating, trembling or seizures. These symptoms can occur when too much JELIDO® (lidocaine hydrochloride jelly) is used at one time and when large amounts are used over a long period of time.

If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, talk to your healthcare professional.

What should I tell my doctor before I use JELIDO®?

To help avoid side effects and ensure proper use, talk to your healthcare professional about any health conditions or problems you may have, including if you:

  • Take other medications, including ones you can buy without a prescription
  • Have problems with your heart, including:
    • A slower than normal heart rate (bradycardia)
    • Irregular heartbeat (arrhythmia)
  • Ever had a bad, unusual, or allergic reaction to JELIDO® or any other medicines ending with “-caine”
  • Think you may be allergic or sensitive to any ingredients in JELIDO® (see list of ingredients)
  • Have an infection, skin rash, cut, or wound at or near the area where you want to apply JELIDO®
  • Have a skin condition that is severe or that covers a large area
  • Have problems with your liver or kidneys
  • Have epilepsy
  • You or someone in your family has been diagnosed with porphyria, a disorder that can cause nerve or skin problems
  • Are experiencing shock
  • Are pregnant, plan to become pregnant, or are breastfeeding
What if I have a history of urinary tract infections (UTIs)? Can I use JELIDO® for catheterization?

Be sure to tell your healthcare professional if you have a history of UTIs. They can help decide whether JELIDO® is right for you or suggest another treatment that’s best for you.

What should I do if I use too much JELIDO® or suspect an overdose?

If you think you, or a person you are caring for, have used too much JELIDO®, contact a healthcare professional, hospital emergency department, regional poison control centre, or Health Canada’s toll-free number, 1-844 POISON-X (1-844-764-7669), immediately, even if there are no signs or symptoms.

Symptoms of an overdose include:

  • Numbness of the lips and around the mouth
  • Feeling lightheaded
  • Dizziness
  • Blurred vision
  • Trembling
  • Seizures
  • Losing consciousness
Can JELIDO® be injected?

No. JELIDO® is not to be injected.

Can JELIDO® interact with other medications that I am taking?

Yes. The following medicines may interact with JELIDO®:

  • Drugs you can buy without a prescription
  • Anti-arrhythmic drugs used to treat heart problems (e.g., mexiletine, amiodarone). Your doctor should monitor you carefully and send you for an electrocardiogram (ECG) if you are taking JELIDO® and amiodarone
  • Other local anaesthetics
  • Erythromycin, used to treat bacterial infections
  • Itraconazole, used to treat fungal infections
  • If you are going to use high doses of JELIDO® for a long time, the following medications may interact with it:
    • Propranolol, used to treat heart problems
    • Cimetidine, used to treat gastrointestinal problems
    • Fluvoxamine, used to treat depression
  • Other medicines that may cause methemoglobinemia, including sulfonamides, acetanilide, aniline dyes, benzocaine (or other “-caine” type anaesthetics), chloroquine, dapsone, naphthalene, nitrates or nitrites, nitrofurantoin, nitroglycerin, nitroprusside, pamaquine, para-aminosalicylic acid, phenacetin, phenobarbital, phenytoin, primaquine, quinine, and high doses of acetaminophen

Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements, or alternative medicines.

If you have any questions about the medications you are taking, talk to your doctor or pharmacist.

How do I store JELIDO®?

Store JELIDO® at room temperature (15 °C to 30 °C). Protect from freezing. Do not keep JELIDO® in the bathroom medicine cabinet or other warm, moist places.

Store in the original package.

Keep out of the reach and sight of children.

Do not use JELIDO® after the expiry date marked on the package.

How do I report JELIDO® side effects?

You can report any suspected side effects associated with the use of health products to Health Canada by:

NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.

Medication information

Consult the JELIDO® information leaflet.

Download

JELIDO® (lidocaine hydrochloride jelly) is a topical jelly that is used in adults and children (2 years of age and older) to lubricate and numb (produce a temporary loss of feeling) the skin. It is used:

  • By your doctor before certain types of medical procedures
  • To help relieve pain from inflammation of the bladder and urethra

Consult the Product Monograph for contraindications, warnings, precautions, adverse reactions, drug interactions, dosing, and conditions of clinical use. The Product Monograph is also available by calling 1-888-550-6060.

PENDOPHARM

JELIDO and UROSAFETIP are registered trademarks of Finchley Research & Development Inc., used under license. INSTILLAGEL is a registered trademark of FARCO-PHARMA GmbH, used under license. PENDOPHARM and its logo are registered trademarks of Finchley Research & Development Inc., used under license.

*Registered trademarks are the property of their respective owners.

© 2026 PENDOPHARM®. All rights reserved.

Publication date: 29-10-2026

Contact us

For any questions about our products or further information about our company, please do not hesitate to contact us.

JELIDO® and INSTILLAGEL® are available at select specialty pharmacies and by special order at most pharmacy outlets. No prescription is required.

6111 Royalmount AvenueMontreal (Quebec)H4P 2T4, CanadaTelephone+1 (514) 340-5045Fax+1 (866) 926-7654 or +1 (514) 733-9684

MED INFO

Toll-free Telephone: +1 (888) 550-6060
Fax: +1 (514) 340-0164
E-mail: medinfo@pharmascience.com

PHARMACOVIGILANCE:

By Telephone: +1 (888) 550-6060
By Fax: +1 (866) 551-1939
By E-mail: adr@pharmascience.com

For Medical and Scientific Information Services, Adverse Event Report, and Customer Service, please visit our website at https://pendopharm.com/contact/.

JELIDO® important safety information

Indications and clinical use:

JELIDO® (lidocaine hydrochloride jelly) is indicated for:

  • Surface anaesthesia and lubrication for:
    • The male and female urethra during cystoscopy, catheterization, exploration by sound, and other endourethral operations
    • Nasal and pharyngeal cavities in endoscopic procedures such as gastroscopy and bronchoscopy
    • Proctoscopy and rectoscopy
    • Tracheal intubation
  • Symptomatic treatment of pain in connection with cystitis and urethritis

Pediatrics (2–18 years of age): Children should be given reduced doses commensurate with their age, weight, and physical condition.

Pediatrics (< 2 years of age): Lidocaine should be used with caution in children younger than two years of age as there are insufficient data to support the safety and efficacy of this product in this patient population at this time.

Geriatrics (> 65 years of age): Elderly patients should be given reduced doses commensurate with their age and physical condition.

Contraindications:

  • Patients who are hypersensitive to this drug or to any ingredient in the formulation, including any non-medicinal ingredient, or any component of the container
  • Patients with a known history of hypersensitivity to local anaesthetics of the amide type or to other components in the formulation
  • Patients with congenital or idiopathic methemoglobinemia
  • Infants ≤ 12 months of age who require treatment with methemoglobin-inducing agents (e.g., sulfonamides)
  • Patients with glucose-6-phosphate dehydrogenase deficiency, which makes them more susceptible to drug-induced methemoglobinemia

Most serious warnings and precautions:

  • PATIENTS SHOULD BE INSTRUCTED TO STRICTLY ADHERE TO THE RECOMMENDED DOSAGE: EXCESSIVE DOSAGE, OR SHORT INTERVALS BETWEEN DOSES, CAN RESULT IN HIGH PLASMA LEVELS OF LIDOCAINE OR ITS METABOLITES AND SERIOUS, AS WELL AS LIFE-THREATENING, ADVERSE EFFECTS, including methemoglobinemia.
  • Use in children and infants (< 3 months): Ensure the caregiver understands to limit the dose and area of application and to prevent accidental ingestion. Children should be closely observed during and after use of lidocaine as they are at greater risk than adults for serious adverse events (e.g., methemoglobinemia).

Other relevant warnings and precautions:

  • Lowest effective dose should be used
  • Avoid contact with eyes
  • Potential triggering agent for familial malignant hyperthermia
  • In patients under general anaesthesia who are paralyzed, higher plasma concentrations may occur than in spontaneously breathing patients
    • Unparalyzed patients are more likely to swallow a large proportion of the dose, which then undergoes considerable first-pass hepatic metabolism following absorption from the gut
  • Endotracheal tube lubrication
    • Avoid introduction of the jelly into the lumen of the tube
    • Do not use to lubricate the endotracheal stylettes
  • Topical anaesthetics used in the mouth may enhance the danger of aspiration
  • Numbness of the tongue or buccal region may enhance unintentional biting trauma
  • May temporarily impair locomotion or alertness
  • Use with caution in patients with:
    • Sepsis
    • Traumatized mucosa at the area of application
    • Epilepsy
    • Severe shock
    • Bradycardia
    • Impaired cardiovascular function
    • Hepatic disease or impaired renal function
    • Known drug sensitivities
  • Exercise caution when driving and operating machinery
  • Exercise caution with use in all porphyric patients
  • Reduced doses should be given in debilitated patients, acutely ill patients, and patients with sepsis
  • Care should be taken during early pregnancy

For more information:

Consult the Product Monograph for important information relating to adverse events, drug interactions, and dosing that has not been discussed in this piece. The Product Monograph is also available by calling 1-888-550-6060.